experimental allergic encephalomyelitis (eae), a demyelinating disease induced in the animals parallels multiple sclerosis in human in several aspects, provides a useful model to investigate multiple sclerosis. in this study, we have therefore used this model to study functions of nerve growth factor (ngf) in eae. ngf with considerable effects on neuron survival, proliferation and differentiati...

introduction: carbon nanotubes (cnts) have shown enormous potential in neuroscience. nerve growth factor (ngf)-cnts complex promotes the neuronal growth, however, the underlying mechanism(s) have remained elusive. based on the interplay between ngf and the endocannabinoid system, involvement of the neuroprotective endocannabinoid, 2-arachidonoyl glycerol (2-ag), was investigated in the mechanis...

meningitis is one of the most common infectious cerebral nervous system (cns), defined as an inflammation of the meninges. it is clinically categorized into a chronic and acute based on the acuity of symptoms. vomiting, bulging fontanel and fever are the main symptoms in the patients with meningitis. bacterial meningitis is a severe, potentially life-threatening infection that is associated wit...

conclusions this study shows that bdnf and ngf expression decreases in diabetic neuropathy. however, this decrease can be reversed through endurance training. these results also indicate that endurance training may have a potential role in compensating for neurotrophin deficiency following diabetic neuropathy. objectives this experimental study was designed and carried out at the tarbiat modare...

objective(s):althoughroutinely applied in assisted reproductive technology, human sperm cryopreservation is not a completely successful procedure. adverse effects of cryopreservation on the fertilization capacity, motility, morphology, and viability of spermatozoa have been proven; cryopreservation has also shown a role in sperm dna fragmentation and infertility. the post-thaw survival of sperm...

objective(s) psychotropic medications produce their effects, in part, through increasing neurotrophin levels in the brain. since studies concerning nerve growth factor (ngf) analysis have been limited in scope, in the current experiments we investigated the effects of diverse psychotropic agents on ngf protein levels in various brain regions of rat. materials and methods male wistar rats receiv...

Objective(s):Althoughroutinely applied in assisted reproductive technology, human sperm cryopreservation is not a completely successful procedure. Adverse effects of cryopreservation on the fertilization capacity, motility, morphology, and viability of spermatozoa have been proven; cryopreservation has also shown a role in sperm DNA fragmentation and infertility. The post-thaw survival of sperm...